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NFAT

Nuclear Factor of Activated T Cells c1 (NFATc1) Antibody(Z5321)

anti-NFAT c1 antibody(Z5321)

NFATc1 is a key transcription factor acting downstream of calcium signaling pathways. It plays a central role in T-cell activation (immune response) and osteoclast differentiation (bone metabolism). By regulating the expression of specific genes, NFATc1 controls these processes and is considered a therapeutic target for immune disorders and osteoporosis.

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Volume 200 µL (0.5 mg/mL)
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Product code 2ATFA02
manufacturer Institute of Immunology Co., Ltd.
Clone Z5321
Application WB
Isotype IgG2a
Host animal mouse
Reactivity human
Concentration 0.5 mg/mL
Immunogen  human NFATc1 protein (134-223 a.a.)
Buffer PBS, pH7.2 (containing 0.1% NaN3)
Conjugate Unlabeled
Storage Store at 4 °C for short-term use (up to 2 weeks) and at –20 °C for long-term
References 1) Suehiro J, et al: J Biol Chem, 289(42): 29044-29059, 2014.

Antibody